Does phenylephrine affect sleep?

Phenylephrine relieves congestion of the nasal passages and is found in many cold and flu remedies. There is some controversy over whether it works at the dosages usually found in over-the-counter products. Sleeplessness is a common side effect.

Do nasal decongestants keep you awake?

Decongestants may keep you awake and are usually taken during the day. Nasal sprays are less likely to have that side effect and may be helpful at night for congestion. Decongestants can also raise blood pressure. So if your BP is high already, or you’ve got heart disease, check with your doctor before you use them.

Is phenylephrine non drowsy?

Each caplet contains phenylephrine HCl decongestant for effective, non-drowsy symptom relief.

Does phenylephrine make you anxious?

severe dizziness or nervousness; sleep problems (insomnia); or. increased blood pressure”severe headache, blurred vision, pounding in your neck or ears.

Will phenylephrine keep you awake at night?

Sudafed Pe (Phenylephrine) Clears your sinuses. Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don’t forget your photo ID or you won’t be able to buy it in the drugstore.

Who should not take phenylephrine?

do not take phenylephrine if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 2 weeks.

Is it safe to take phenylephrine everyday?

Phenylephrine nasal is usually used every 4 hours. Follow the directions on the medicine label. Never use more of this medicine than directed on the label or prescribed by your doctor. Using phenylephrine nasal too long can damage the lining of your nasal passages and lead to chronic nasal congestion.

When should phenylephrine be avoided shock?

Phenylephrine is recommended to not be used for septic shock, except when 1) septic shock persists despite the use of 2 or more inotrope/vasopressor agents along with low-dose vasopressin; 2) cardiac output is known to be high, or 3) norepinephrine is considered to have already caused serious arrhythmias (Grade 1C).

What does phenylephrine do to the body?

Phenylephrine is used for the temporary relief of stuffy nose, sinus, and ear symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). This medication works by decreasing swelling in the nose and ears, thereby lessening discomfort and making it easier to breathe.

How long does phenylephrine stay in the system?

The elimination half life of phenylephrine is about 2.5 to 3.0 hours.

How long can you use phenylephrine?

Stop use and ask a doctor if: Your symptoms last for more than seven days when using an oral medicine containing phenylephrine. Topical nasal decongestants should not be used for more than three days.

Does phenylephrine affect heart rate?

Oral phenylephrine has a minimal direct effect on heart rate or cardiac output but, as a vasoconstrictor, can increase systolic and diastolic blood pressure at high doses, and thus cause reflex bradycardia.

Does phenylephrine make you Bradycardic?

Learning Objectives: Phenylephrine is a synthetic catecholamine that increases systemic vascular resistance via activation of alpha receptors. A known side effect of phenylephrine is reflex bradycardia due to activation of the baroreceptor.

Will phenylephrine raise blood pressure?

To keep your blood pressure in check, avoid over-the-counter decongestants and multisymptom cold remedies that contain decongestants ” such as pseudoephedrine, ephedrine, phenylephrine, naphazoline and oxymetazoline. Also, check the label for high sodium content, which can also raise blood pressure.

Why does phenylephrine decrease heart rate?

Most textbooks and review articles contain a table showing a reduction in cardiac output from phenylephrine (example above). The usual explanation is that phenylephrine increases systemic vascular resistance (afterload), which makes it harder for the heart to pump blood forward.

What is the difference between ephedrine and phenylephrine?

Ephedrine increases heart rate and contractility of the heart muscle and is likely to increase oxygen demand. Phenylephrine reduces heart rate while maintaining blood pressure which may result in a more favorable oxygen supply demand ratio.

Why does phenylephrine increase BP?

Phenylephrine is a selective α1-adrenergic receptor agonist that increases blood pressure mainly by increasing systemic vascular resistance, without an associated increase in myocardial contractility.

Is phenylephrine the same as pseudoephedrine?

You may know pseudoephedrine and phenylephrine from their use in Sudafed products. Sudafed contains pseudoephedrine, while Sudafed PE contains phenylephrine. The drugs are also available in several combinations with other over-the-counter cough and cold medications. These drugs are both nasal decongestants.

Which is safer phenylephrine or pseudoephedrine?

The study concluded that there was no significant difference between phenylephrine and placebo. However, pseudoephedrine provided a significant difference in nasal decongestion as compared to both placebo and phenylephrine. These results suggest that pseudoephedrine is the superior nasal decongestant.

Is pseudoephedrine more effective than phenylephrine?

Yes. Most patients and healthcare providers will agree that Sudafed (pseudoephedrine) is more effective for congestion than its counterpart Sudafed PE (phenylephrine). This is likely due to the fact that the intestines will absorb only about 38% of the amount of Sudafed PE in one tablet, while Sudafed is 100% absorbed.

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